Continuedly affected by the pandemic covid-19, 2021 10th International Conference on Innovation, Knowledge, and Management  has been held as a fully virtual conference. The safety and well-being of the participants is our top priority, who have joined the conference and presented their papers online. On behalf of the organizing committee, we'd like to thank all the keynote speakers, invited speakers and authors. We believe we'll all survive this health crisis and get back to our normal life soon. We look forward to seeing you at a face-to-face conference in near future.